RAD53 (YPL153C)

YPL153C / RAD53

Aliases: YPL153C, RAD53, LSD1, MEC2, SPK1
Protein kinase, required for cell-cycle arrest in response to DNA damage; activated by trans autophosphorylation when interacting with hyperphosphorylated Rad9p; also interacts with ARS1 and plays a role in initiation of DNA replication
Note: On Cytoscape figures, arrows represent only bait-prey directionality, not functional directionality.