Aliases: YDL042C, SIR2, MAR1

[SGD] [BioGRID] [GeneDB] [Ensembl] [Entrez Gene]

Conserved NAD+ dependent histone deacetylase of the Sirtuin family involved in regulation of lifespan; plays roles in silencing at HML, HMR, telomeres, and the rDNA locus; negatively regulates initiation of DNA replication